Exploration of empirical Bayes hierarchical modeling for the analysis of genome-wide association study data
نویسندگان
چکیده
منابع مشابه
Exploration of empirical Bayes hierarchical modeling for the analysis of genome-wide association study data.
In the analysis of genome-wide association (GWA) data, the aim is to detect statistical associations between single nucleotide polymorphisms (SNPs) and the disease or trait of interest. These SNPs, or the particular regions of the genome they implicate, are then considered for further study. We demonstrate through a comprehensive simulation study that the inclusion of additional, biologically r...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2011
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxq072